Re-Evaluating Cell-Cycle Regulation by E2Fs

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چکیده

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Re-Evaluating Cell-Cycle Regulation by E2Fs

Activation of E2F transcription factors is thought to drive the expression of genes essential for the transition of cells from G1 to S phase and for the initiation of DNA replication. However, this textbook view of E2Fs is increasingly under challenge. Here we discuss an alternative model for how E2Fs may work.

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ژورنال

عنوان ژورنال: Cell

سال: 2006

ISSN: 0092-8674

DOI: 10.1016/j.cell.2006.11.019